First transcatheter leadless pacemaker implantation in a pediatric patient with a genetic disease

Wörmann J, Lüker J, Plenge T, van den Bruck JH, Steven D, Sultan A.Herzschrittmacherther Elektrophysiol. 2020 Jun;31(2):235-237. doi: 10.1007/s00399-020-00685-9. Epub 2020 May 5.PMID: 32372230 English.


A pediatric patient suffering from Marden-Walker syndrome, a rare genetic disease, was referred to the authors’ hospital for syncope due to bradycardia. Since this disease is associated with severe joint contractures, a transcatheter leadless pacing system (TPS) was chosen. Despite the small body size and complex anatomy, TPS implantation was feasible, demonstrating that it is a safe alternative in difficult venous access compared to a conventional pacemaker with increased risk of lead complications in these patients.