Cortisol/cortisone levels and quality of life in individuals with pulmonary arterial hypertension

Tulloh R, Quek FF, Stevenson K, Garratt V, Turner-Cobb JM.Pulm Circ. 2020 May 18;10(2):2045894020924325. doi: 10.1177/2045894020924325. eCollection 2020 Apr-Jun.PMID: 32523685 Free PMC article



Individuals with pulmonary arterial hypertension experience debilitating symptoms and psychological distress which may influence their cortisol regulation. We describe associations between diurnal salivary cortisol/cortisone levels and quality of life in adults with pulmonary arterial hypertension. Findings suggest potential clinical utility of cortisol/cortisone assessment as applied to a pulmonary arterial hypertension population.


Fig. 1. Cortisol (a) and Cortisone (b) levels by patient participants; measured at awakening, 30 min later and in the evening in people with PAH; displays rise and fall, diurnal rhythm. Data show n = 18 participants (a) and n = 19 (b).