Fetal Cardiology May 2021 Abstracts

1. Setd5 is required in cardiopharyngeal mesoderm for heart development and its haploinsufficiency is associated with outflow tract defects in mouse.

Cheung MY, Roberts C, Scambler P, Stathopoulou A.Genesis. 2021 May 29:e23421. doi: 10.1002/dvg.23421. Online ahead of print.PMID: 34050709

2. HUMAN LATERALITY DISORDERS: PATHOGENESIS, CLINICAL MANIFESTATIONS, DIAGNOSIS, AND MANAGEMENT.

Soofi M, Alpert MA, Barbadora J, Mukerji B, Mukerji V.Am J Med Sci. 2021 May 27:S0002-9629(21)00190-7. doi: 10.1016/j.amjms.2021.05.020. Online ahead of print.PMID: 34052215 Review.

3. The yield of chromosomal microarray in pregnancies with congenital cardiac defects and normal NIPS.

Sagi-Dain L, Singer A, Segel R, Berger R, Kanengisser-Pines B, Maya I.Am J Obstet Gynecol. 2021 May 27:S0002-9378(21)00588-3. doi: 10.1016/j.ajog.2021.05.022. Online ahead of print.PMID: 34052193

4. CNVs in the 22q11.2 Chromosomal Region Should Be an Early Suspect in Infants with Congenital Cardiac Disease.

Pineda T, Zarante I, Paredes AC, Rozo JP, Reyes MC, Moreno-Niño OM.Clin Med Insights Cardiol. 2021 May 24;15:11795468211016870. doi: 10.1177/11795468211016870. eCollection 2021.PMID: 34104029 Free PMC article.

5. Mosaic duplication of 8q24.1q24.3 detected by chromosomal microarray but not karyotyping in two unrelated fetuses with cardiac defects.

Lin S, Huang S, Ou X, Gu H, Wang Y, Li P, Zhou Y.Mol Cytogenet. 2021 May 18;14(1):26. doi: 10.1186/s13039-021-00544-3.PMID: 34006293 Free PMC article.

6. Impact of Socioeconomic Status, Race and Ethnicity, and Geography on Prenatal Detection of Hypoplastic Left Heart Syndrome and Transposition of the Great Arteries.

Krishnan A, Jacobs MB, Morris SA, Peyvandi S, Bhat AH, Chelliah A, Chiu JS, Cuneo BF, Freire G, Hornberger LK, Howley L, Husain N, Ikemba C, Kavanaugh-McHugh A, Kutty S, Lee C, Lopez KN, McBrien A, Michelfelder EC, Pinto NM, Schwartz R, Stern KWD, Taylor C, Thakur V, Tworetzky W, Wittlieb-Weber C, Woldu K, Donofrio MT; Fetal Heart Society.Circulation. 2021 May 25;143(21):2049-2060. doi: 10.1161/CIRCULATIONAHA.120.053062. Epub 2021 May 17.PMID: 33993718

7. Fetal growth of left-sided structures and postnatal surgical outcomes in the “borderline” left heart varies by cardiac phenotype.

Venardos A, Colquitt J, Morris SA.Ultrasound Obstet Gynecol. 2021 May 16. doi: 10.1002/uog.23689. Online ahead of print.PMID: 33998097

8. Prenatal cardiac biometries and flow assessments in fetuses at 20 weeks with a bicuspid aortic valve compared to healthy controls: a multicenter, cohort study.

Vedel C, Rode L, Bundgaard H, Iversen K, Jørgensen FS, Petersen OB, Sillesen AS, Sundberg K, Vejlstrup N, Zingenberg H, Tabor A, Ekelund CK.Ultrasound Obstet Gynecol. 2021 May 16. doi: 10.1002/uog.23670. Online ahead of print.PMID: 33998082

9. Perinatal diagnosis of a fetus with an unbalanced translocation 46,XY,der(10)t(6;10)(p22;q26.1) with multiple malformations:a case report and literature review.

Ishibashi M, Watanabe T, Kyozuka H, Yamaguchi A, Sato K, Sato M, Go H, Fujimori K.Fukushima J Med Sci. 2021 May 15. doi: 10.5387/fms.2020-28. Online ahead of print.PMID: 33994433 Free article.

10. Fetal Diagnosis is Associated with Improved Perioperative Condition of Neonates Requiring Surgical Intervention for Coarctation.

Houshmandi MM, Eckersley L, Fruitman D, Mills L, Power A, Hornberger LK.Pediatr Cardiol. 2021 May 14. doi: 10.1007/s00246-021-02634-w. Online ahead of print.PMID: 33988733

11. Factors That Influence Parents’ Decision Making Regarding Termination of Pregnancy After Prenatal Diagnosis of Fetal Congenital Heart Disease.

Gendler Y, Birk E, Tabak N, Koton S.J Obstet Gynecol Neonatal Nurs. 2021 May 12:S0884-2175(21)00057-5. doi: 10.1016/j.jogn.2021.04.002. Online ahead of print.PMID: 33991490

12. FGD5-AS1 Is a Hub lncRNA ceRNA in Hearts With Tetralogy of Fallot Which Regulates Congenital Heart Disease Genes Transcriptionally and Epigenetically.

Zhang X, Gao Y, Zhang X, Zhang X, Xiang Y, Fu Q, Wang B, Xu Z.Front Cell Dev Biol. 2021 May 11;9:630634. doi: 10.3389/fcell.2021.630634. eCollection 2021.PMID: 34046402 Free PMC article.

13. Molecular and cellular basis of embryonic cardiac chamber maturation.

Dong Y, Qian L, Liu J.Semin Cell Dev Biol. 2021 May 11:S1084-9521(21)00095-1. doi: 10.1016/j.semcdb.2021.04.022. Online ahead of print.PMID: 33994094 Review.

14. Maternal psychological stress during pregnancy and risk of congenital heartdisease in offspring: A systematic review and meta-analysis.

Gu J, Guan HB.J Affect Disord. 2021 May 8;291:32-38. doi: 10.1016/j.jad.2021.05.002. Online ahead of print.PMID: 34023745 Review.

15. Introduction to the special focus on the development of the autonomic nervous system.

Siegel RE, Watanabe M.Birth Defects Res. 2021 May 8. doi: 10.1002/bdr2.1902. Online ahead of print.PMID: 33963818 No abstract available.

16. Single cell RNA sequencing approaches to cardiac development and congenitalheart disease.

Samad T, Wu SM.Semin Cell Dev Biol. 2021 May 15:S1084-9521(21)00096-3. doi: 10.1016/j.semcdb.2021.04.023. Online ahead of print.PMID: 34006454 Review.

17. Of form and function: Early cardiac morphogenesis across classical and emerging model systems.

Shewale B, Dubois N.Semin Cell Dev Biol. 2021 May 14:S1084-9521(21)00098-7. doi: 10.1016/j.semcdb.2021.04.025. Online ahead of print.PMID: 33994301 Review.

18. Epigenetics and Heart Development.

George RM, Firulli AB.Front Cell Dev Biol. 2021 May 6;9:637996. doi: 10.3389/fcell.2021.637996. eCollection 2021.PMID: 34026751 Free PMC article. Review.

19. Prenatal stomach position predicts gastrointestinal morbidity at 2 years in fetuses with left-sided congenital diaphragmatic hernia.

Cordier AG, Laup L, Letourneau A, Le Sache N, Fouquet V, Senat MV, Perrotin F, Rosenblatt J, Sananes N, Jouannic JM, Benoist G, Jani JC, Benachi A.Ultrasound Obstet Gynecol. 2021 Jun;57(6):959-967. doi: 10.1002/uog.22086. Epub 2021 May 5.PMID: 32462707

20. Cost-effectiveness of prenatal screening methods for congenital heart defectsin pregnancies conceived by in-vitro fertilization.

Chung EH, Lim SL, Havrilesky LJ, Steiner AZ, Dotters-Katz SK.Ultrasound Obstet Gynecol. 2021 Jun;57(6):979-986. doi: 10.1002/uog.22048. Epub 2021 May 5.PMID: 32304621

21. The Interaction Analysis of SNP Variants and DNA Methylation Identifies Novel Methylated Pathogenesis Genes in Congenital Heart Diseases.

Wang J, Ma X, Zhang Q, Chen Y, Wu D, Zhao P, Yu Y.Front Cell Dev Biol. 2021 May 4;9:665514. doi: 10.3389/fcell.2021.665514. eCollection 2021.PMID: 34041244 Free PMC article.

22. Urine metabolomic biomarkers for prediction of isolated fetal congenital heartdefect.

Friedman P, Yilmaz A, Ugur Z, Jafar F, Whitten A, Ustun I, Turkoglu O, Graham S, Bahado Singh R.J Matern Fetal Neonatal Med. 2021 May 4:1-8. doi: 10.1080/14767058.2021.1914572. Online ahead of print.PMID: 33944672

23. Reference Ranges for Pulsed-Wave Doppler of the Fetal Cardiac Inflow and Outflow Tracts from 13 to 36 Weeks’ Gestation.

Zidere V, Vigneswaran TV, Syngelaki A, Charakida M, Allan LD, Nicolaides KH, Simpson JM, Akolekar R.J Am Soc Echocardiogr. 2021 May 3:S0894-7317(21)00467-3. doi: 10.1016/j.echo.2021.04.017. Online ahead of print.PMID: 33957251

24. An ensemble of neural networks provides expert-level prenatal detection of complex congenital heart disease.

Arnaout R, Curran L, Zhao Y, Levine JC, Chinn E, Moon-Grady AJ.Nat Med. 2021 May;27(5):882-891. doi: 10.1038/s41591-021-01342-5. Epub 2021 May 14.PMID: 33990806

25. Deep learning for detecting congenital heart disease in the fetus.

Morris SA, Lopez KN.Nat Med. 2021 May;27(5):764-765. doi: 10.1038/s41591-021-01354-1.PMID: 33990805 No abstract available.

26. Prenatal diagnosis of maternal uniparental disomy 16 associated with mosaic trisomy 16 at amniocentesis, and pericardial effusion and intrauterine growth restriction in the fetus.

Chen CP, Ko TM, Chern SR, Wu PS, Chen SW, Wu FT, Chen YY, Town DD, Chen LF, Wang W.Taiwan J Obstet Gynecol. 2021 May;60(3):534-539. doi: 10.1016/j.tjog.2021.03.027.PMID: 33966743 Free article.

27. Toward Eliminating Perinatal Comfort Care for Prenatally Diagnosed Severe Congenital Heart Defects: A Vision.

Stephens EH, Dearani JA, Qureshi MY, Segura LG, Arendt KW, Bendel-Stenzel EM, Ruano R.Mayo Clin Proc. 2021 May;96(5):1276-1287. doi: 10.1016/j.mayocp.2020.08.029.PMID: 33958058 Review.

28. Reliability of Fetal Echocardiography in Predicting Postnatal Critical Hypoxia in Patients with Transposition of Great Arteries and Intact Ventricular Septum.

Masci M, Pasquini L, Alsaied T, Di Chiara L, Formigari R, Galletti L, Campanale CM, Romiti A, Bonito M, Bagolan P, Toscano A.Pediatr Cardiol. 2021 May 29. doi: 10.1007/s00246-021-02642-w. Online ahead of print.PMID: 34052858

29. Prenatal diagnosis, associated findings and postnatal outcome of fetuses with truncus arteriosus communis (TAC).

Abel JS, Berg C, Geipel A, Gembruch U, Herberg U, Breuer J, Brockmeier K, Gottschalk I.Arch Gynecol Obstet. 2021 May 24. doi: 10.1007/s00404-021-06067-x. Online ahead of print.PMID: 34028563

30. Prenatal nicotine exposure was associated with long-term impact on the cardiovascular system and regulation-Review.

Nordenstam F.Acta Paediatr. 2021 May 13. doi: 10.1111/apa.15914. Online ahead of print.PMID: 33982809 Review.

31. Prenatal sonography of the foramen ovale predicts urgent balloon atrial septostomy in neonates with complete transposition of the great arteries.

Gatta AND, Contro E, Lenzi J, Balducci A, Gargiulo G, Bodnar T, Palleri D, Bonetti S, Hasan T, Donti A, Ragni L, Angeli E, Bartolacelli Y, Larcher L, Pilu G, Perolo A.Am J Obstet Gynecol MFM. 2021 May 6:100379. doi: 10.1016/j.ajogmf.2021.100379. Online ahead of print.PMID: 33965655

32. Foetal cardiac function in third trimester pregnancies with reduced fetal movements.

Saglam A, Derwig I, Gul M, Kasap B, Yilmaz N, Sezik M, Celik O, Tiryaki S, Özcil MD, Sipahioğlu H, İnci S, Demircan F.J Obstet Gynaecol. 2021 May 2:1-7. doi: 10.1080/01443615.2020.1869706. Online ahead of print.PMID: 33938348

33. Cardiac rhabdomyoma with hydrops fetalis: Prenatal management by abdominal drainage.

Emeline L, Nadir B, Claire B, Claudine LV.Taiwan J Obstet Gynecol. 2021 May;60(3):551-553. doi: 10.1016/j.tjog.2021.03.030.PMID: 33966747 Free article.

34. Aortopulmonary window: Clues to fetal diagnosis.

Bhalgat PS, Nabi F, Ray S.Ann Pediatr Cardiol. 2021 Apr-Jun;14(2):247-248. doi: 10.4103/apc.APC_42_20. Epub 2021 Feb 16.PMID: 34103873 Free PMC article.