Fetal CHD and perinatal outcomes


Ge CJ, Mahle AC, Burd I, Jelin EB, Sekar P, Jelin AC.
Cardiol Young. 2020 Apr 20:1-6. doi: 10.1017/S1047951120000785. [Epub ahead of print] PMID: 32308170
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Objective: To evaluate delivery management and outcomes in fetuses prenatally diagnosed with CHD.

Study design: A retrospective cohort study was conducted on 6194 fetuses (born between 2013 and 2016), comparing prenatally diagnosed with CHD (170) to those with non-cardiac (234) and no anomalies (5790). Primary outcomes included the incidence of preterm delivery and mode of delivery.

Results: Gestational age at delivery was significantly lower between the CHD and non-anomalous cohorts (38.6 and 39.1 weeks, respectively). Neonates with CHD had a significantly lower birth weights (p < 0.001). There was an approximately 1.5-fold increase in the rate of primary cesarean sections associated with prenatally diagnosed CHD with an odds ratio of 1.49 (95% CI 1.06-2.10).

Conclusions: Our study provides additional evidence that the prenatal diagnosis of CHD is associated with a lower birth weight, preterm delivery, and with an increased risk of delivery by primary cesarean section.